Product Overview
L-NIL dihydrochloride | T25749 | TargetMol Chemicals
CAS: 159190-45-1
Smiles: Cl.Cl.NCCCC[C@H](NCC=N)C(O)=O
Formula: C8H19Cl2N3O2
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: L-NIL HCl is a relatively selective iNOS inhibitor (IC50s: 0.4-3.3, 8-38, and 17-92 µM for iNOS, eNOS, and nNOS). L-NIL effectively inhibits iNOS both in vitro and in vivo. L-NIL has been used to demonstrate a critical role for iNOS in the immune response to infection by the protozoan L. major.
Molecular Weight: 260, 16