Product Overview
Lactacystin | T15702 | TargetMol Chemicals
CAS: 133343-34-7
Smiles: CC(C)[C@H](O)[C@]1(NC(=O)[C@H](C)[C@@H]1O)C(=O)SC[C@H](NC(C)=O)C(O)=O
Formula: C15H24N2O7S
Pathway: Proteases/Proteasome|||Ubiquitination
Target: Proteasome
Receptor: N/A
Bioactivity: Lactacystin is an antibiotic Streptomyces spp. the metabolite and is an effective and selective proteasome inhibitor (IC50: 4.8 μM for 20S proteasome). Lactacystin inhibits cell growth and induces neurite outgrowth and also inhibits the lysosomal enzyme cathepsin A.
Molecular Weight: 376, 42