Product Overview
Larotrectinib | T5995 | TargetMol Chemicals
CAS: 1223403-58-4
Smiles: O[C@H]1CCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Formula: C21H22F2N6O2
Pathway: Apoptosis|||Tyrosine Kinase/Adaptors
Target: Apoptosis|||Trk receptor
Receptor: N/A
Bioactivity: Larotrectinib is an orally administered inhibitor of the TRK kinase and is highly selective only for the TRK family of receptors(IC50s = 2-20 nM).
Molecular Weight: 428, 444
