Lazertinib | T4485

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€165.00 - €1,001.00
SKU:
TMC-T4485
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Product Overview

Lazertinib | T4485 | TargetMol Chemicals

CAS: 1903008-80-9

Smiles: COc1cc(N2CCOCC2)c(NC(=O)C=C)cc1Nc1nccc(n1)-n1cc(CN(C)C)c(n1)-c1ccccc1

Formula: C30H34N8O3

Pathway: Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors

Target: EGFR

Receptor: N/A

Bioactivity: Lazertinib is an effective, highly mutant-selective and irreversible EGFR-TKI with IC50 values of 1.7 nM, 2 nM, 5 nM, 20.6 nM and 76 nM for Del19/T790M, L858R/T790M, Del19, L85R and Wild type EGFR respectively.

Molecular Weight: 554, 655

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