Product Overview
LCB 03-0110 dihydrochloride | T32613 | TargetMol Chemicals
CAS: T32613
Smiles: OC1=CC=CC(NC2=C3C(C=C(C4=CC=CC(CN5CCOCC5)=C4)S3)=NC=C2)=C1.[H]Cl.[H]Cl
Formula: C24H25Cl2N3O2S
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: LCB 03-0110 Dihydrochloride is a potent inhibitor of the c-Src kinase (IC50 = 1.3 nM) and tyrosine kinases in the BTK and SYK family, as well as in the DDR2 family. It inhibits LPS-induced activation of macrophages and TGF-β1-induced activation of fibroblasts in vitro, inhibits activation of macrophages and fibroblasts, and inhibits scarring in wound healing models.
Molecular Weight: 490, 44
