Product Overview
LEI110 | T9753 | TargetMol Chemicals
CAS: 2313525-90-3
Smiles: O=C(CCCc1ccccc1)C(NCCc(cc1)ccc1Oc1ncc(C(F)(F)F)cc1)=O
Formula: C25H23F3N2O3
Pathway: Metabolism
Target: Phospholipase
Receptor: N/A
Bioactivity: LEI110 is a potent Phospholipase A2, group XVI (PLA2G16) inhibitor with an Ki value of 20 nM. LEI110 is a selective pan-inhibitor of the HRASLS family of thiol hydrolases (i.e., PLA2G16, HRASLS2, RARRES3 and iNAT).
Molecular Weight: 456, 46