Product Overview
Levofloxacin hydrate | T1451 | TargetMol Chemicals
CAS: 138199-71-0
Smiles: O.C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c2n1cc(C(O)=O)c3=O.C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c2n1cc(C(O)=O)c3=O
Formula: C18H20FN3O4·1/2H2O
Pathway: DNA Damage/DNA Repair|||Microbiology/Virology
Target: DNA gyrase|||Topoisomerase|||Antibacterial|||Antibiotic
Receptor: N/A
Bioactivity: Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inhibiting DNA gyrase (bacterial topoisomerase II), an enzyme required for DNA replication, RNA transcription, and repair of bacterial DNA. Inhibition of DNA gyrase activity leads to blockage of bacterial cell growth.
Molecular Weight: 370, 38
