Licochalcone D | T4518

Licochalcone D | T4518 | TargetMol Chemicals

CAS: 144506-15-0

Smiles: COc1c(O)c(O)ccc1\C=C\C(=O)c1ccc(O)c(CC=C(C)C)c1

Formula: C21H22O5

Pathway: MAPK|||NF-Κb

Target: ERK|||NF-κB

Receptor: N/A

Bioactivity: Licochalcone D may be a potential drug for human melanoma treatment by inhibiting proliferation, inducing apoptosis via the mitochondrial pathway and blocking cell migration and invasion. Licochalcone D has cardioprotective potential against myocardial ischemia/reperfusion injury in langendorff-perfused rat hearts. Licochalcone D has anti-inflammatory activity, it shows suppression ability of nitric oxide (NO) production. Licochalcone D has anti-allergic activity, it suppresses degranulation by decreasing the intracellular Ca2+ level and tyrosine phosphorylation of ERK in RBL-2H3 cells.

Molecular Weight: 354, 402