Product Overview
Lifitegrast sodium | T3977L | TargetMol Chemicals
CAS: 1119276-80-0
Smiles: [Na+].CS(=O)(=O)c1cccc(CC(NC(=O)c2c(Cl)cc3CN(CCc3c2Cl)C(=O)c2ccc3ccoc3c2)C([O-])=O)c1
Formula: C29H23Cl2N2NaO7S
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Lifitegrast sodium (SAR-1118) is an LFA-1 antagonist for the therapy of vascular complications of the eye. It inhibits T cell-mediated inflammation by blocking the binding of two cell surface proteins (lymphocyte function-associated antigen 1 and intercellular adhesion molecule 1), thus reducing overall inflammatory responses.
Molecular Weight: 637, 46