Product Overview
LLY-283 | T15767 | TargetMol Chemicals
CAS: 2040291-27-6
Smiles: [H][C@@]1(O[C@H]([C@H](O)[C@@H]1O)n1ccc2c(N)ncnc12)[C@H](O)c1ccccc1
Formula: C17H18N4O4
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: LLY-283 is an effective and selective inhibitor of protein arginine methyltransferase 5 (PRMT5) (IC50: 22 nM and a Kd: 6 nM for PRMT5:MEP50 complex). It also shows antitumor activity.
Molecular Weight: 342, 355