Product Overview
LM10 | T4410 | TargetMol Chemicals
CAS: 1316695-35-8
Smiles: Fc1ccc2c(\C=C\c3nnn[nH]3)c[nH]c2c1
Formula: C11H8FN5
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: Selective tryptophan 2, 3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively). Exhibits selectivity for TDO over IDO, MAO-A, MAO-B, and a panel of receptors and transporters. Reduces growth of TDO-expressing P815 mastocytoma tumors in mice. Orally bioavailable.
Molecular Weight: 229, 218