Product Overview
Lomitapide | T6267 | TargetMol Chemicals
CAS: 182431-12-5
Smiles: FC(F)(F)CNC(=O)C1(CCCCN2CCC(CC2)NC(=O)c2ccccc2-c2ccc(cc2)C(F)(F)F)c2ccccc2-c2ccccc12
Formula: C39H37F6N3O2
Pathway: Metabolism
Target: CETP
Receptor: N/A
Bioactivity: Lomitapide is a small molecule inhibitor of microsomal triglyceride transfer protein (MTP), an enzyme located in the lumen of the endoplasmic reticulum responsible for absorbing dietary lipids and transferring triglycerides onto apolipoprotein B (apo-B) in the assembly of very-low-density lipoprotein.
Molecular Weight: 693, 734
