Product Overview
Lonafarnib | T6302 | TargetMol Chemicals
CAS: 193275-84-2
Smiles: NC(=O)N1CCC(CC(=O)N2CCC(CC2)[C@H]2c3ncc(Br)cc3CCc3cc(Cl)cc(Br)c23)CC1
Formula: C27H31Br2ClN4O2
Pathway: Autophagy|||GPCR/G Protein|||MAPK|||Metabolism
Target: Raf|||Transferase|||Autophagy|||Ras
Receptor: N/A
Bioactivity: Lonafarnib is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).
Molecular Weight: 638, 83
