Product Overview
LP-922761 | T15780 | TargetMol Chemicals
CAS: 1454808-95-7
Smiles: CN(CCNc1ccc2ncc(-c3ccc(cc3)C(N)=O)n2n1)C(=O)OC(C)(C)C
Formula: C21H26N6O3
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: LP-922761 is an effective, selective, and orally active adapter protein-2 associated kinase 1 (AAK1) inhibitor (IC50: 4.8 nM and a cellular IC50: 7.6 nM). LP-922761 also inhibits BMP-2-inducible protein kinase (BIKE) (IC50: 24 nM). LP-922761 shows no significant activity at cyclin G-associated kinase (GAK), opioid, adrenergic α2, or GABAa receptors.
Molecular Weight: 410, 478
