Product Overview
LP-935509 | T15781 | TargetMol Chemicals
CAS: 1454555-29-3
Smiles: COc1ncccc1-c1cnn2ccc(nc12)N1CCN(CC1)C(=O)OC(C)C
Formula: C20H24N6O3
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: LP-935509 is highly brain-penetrant and reverses fully established pain behavior following the SNL procedure. LP-935509 is an effective inhibitor of BIKE (IC50=14 nM) and a modest inhibitor of cyclin G-associated kinase(GAK, IC50=320 nM). LP-935509 is also a ATP-competitive inhibitor of adapter protein-2 associated kinase 1 (AAK1) (IC50 = 3.3 nM, Ki = 0.9 nM).
Molecular Weight: 396, 451
