Lu AF27139 | T9786

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Product Overview

Lu AF27139 | T9786 | TargetMol Chemicals

CAS: 2097117-06-9

Smiles: O=C(c1c(C(F)(F)F)nc(-c2ncccn2)s1)NC[C@H](c(cc1)ccc1Cl)N1CCOCC1

Formula: C21H19ClF3N5O2S

Pathway: Neuroscience

Target: P2 Receptor

Receptor: N/A

Bioactivity: Lu AF27139 is an effective and selective antagonist of P2X7 receptor (IC50s of 12 and 2.4 nM for human and rat, Kis of 22, 54, and 13 nM for mouse, human, and rat, respectively). Lu AF27139 can be used in CNS diseases studies.

Molecular Weight: 497, 92

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