Product Overview
Lucitanib | T15185 | TargetMol Chemicals
CAS: 1058137-23-7
Smiles: CNC(=O)c1cccc2cc(Oc3ccnc4cc(OCC5(N)CC5)c(OC)cc34)ccc12
Formula: C26H25N3O4
Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors
Target: VEGFR|||FGFR
Receptor: N/A
Bioactivity: Lucitanib is a novel VEGFR and FGFR inhibitor. It potently and selectively inhibits VEGFR1, VEGFR2, VEGFR3, FGFR1 and FGFR2 (IC50s: 7 nM, 25 nM, 10 nM, 17.5 nM, and 82.5 nM, respectively).
Molecular Weight: 443, 503