Product Overview
Lumacaftor | T2595 | TargetMol Chemicals
CAS: 936727-05-8
Smiles: Cc1ccc(NC(=O)C2(CC2)c2ccc3OC(F)(F)Oc3c2)nc1-c1cccc(c1)C(O)=O
Formula: C24H18F2N2O5
Pathway: Autophagy|||Membrane transporter/Ion channel
Target: CFTR|||Autophagy
Receptor: N/A
Bioactivity: VX-809 is a CFTR modulator that corrects the folding and trafficking of CFTR protein. It enhances F508del-CFTR protein maturation in FRT cells (EC50: 100 nM).
Molecular Weight: 452, 414