Product Overview
LX2343 | T4398 | TargetMol Chemicals
CAS: 333745-53-2
Smiles: COc1ccc(Cl)cc1N(CC(=O)Nc1ccc2OCOc2c1)S(=O)(=O)c1ccccc1
Formula: C22H19ClN2O6S
Pathway: Autophagy|||Neuroscience|||PI3K/Akt/mTOR signaling
Target: Beta Amyloid|||Beta-Secretase|||BACE|||PI3K|||Autophagy
Receptor: N/A
Bioactivity: LX2343 is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 μM. LX2343 acts as a non-ATP competitive PI3K inhibitor with an IC50 of 15.99±3.23 μM. LX2343 stimulates autophagy in its promotion of Aβ clearance.
Molecular Weight: 474, 91