Product Overview
LY 345899 | T15827 | TargetMol Chemicals
CAS: 10538-99-5
Smiles: Nc1nc(=O)c2N3C(CN(C3=O)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)CNc2[nH]1
Formula: C20H21N7O7
Pathway: Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Metabolism
Target: DHFR
Receptor: N/A
Bioactivity: LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for MTHFD1).
Molecular Weight: 471, 43
