Product Overview
LY-411575 | T6063 | TargetMol Chemicals
CAS: 209984-57-6
Smiles: C[C@H](NC(=O)[C@@H](O)c1cc(F)cc(F)c1)C(=O)N[C@H]1c2ccccc2-c2ccccc2N(C)C1=O
Formula: C26H23F2N3O4
Pathway: Apoptosis|||Neuroscience|||Proteases/Proteasome|||Stem Cells
Target: Apoptosis|||Gamma-secretase
Receptor: N/A
Bioactivity: LY411575, a potent γ-secretase inhibitor, is with IC50 of 0.078 nM in the membrane and 0.082 nM in cell-based. It also suppresses Notch clevage with IC50 of 0.39 nM.
Molecular Weight: 479, 484
