Product Overview
LY2090314 | T1755 | TargetMol Chemicals
CAS: 603288-22-8
Smiles: Fc1cc2CN(CCn3cc(C4=C(C(=O)NC4=O)c4cnc5ccccn45)c(c1)c23)C(=O)N1CCCCC1
Formula: C28H25FN6O3
Pathway: PI3K/Akt/mTOR signaling|||Stem Cells
Target: GSK-3
Receptor: N/A
Bioactivity: LY2090314, an effective GSK-3α/β inhibitor (IC50: 1.5 nM/0.9 nM), may improve the efficacy of platinum-based chemotherapy regimens. LY2090314 has been used in trials studying the treatment of Leukemia, Advanced Cancer, and Pancreatic Cancer.
Molecular Weight: 512, 545
