Product Overview
LY2109761 | T2123 | TargetMol Chemicals
CAS: 700874-71-1
Smiles: C(CN1CCOCC1)Oc1ccc2c(ccnc2c1)-c1c2CCCn2nc1-c1ccccn1
Formula: C26H27N5O2
Pathway: Autophagy|||Stem Cells
Target: Autophagy|||TGF-beta/Smad
Receptor: N/A
Bioactivity: LY2109761 is a novel selective TGF-β receptor type I/II (TβRI/II) dual inhibitor with Ki of 38 nM and 300 nM, respectively; shown to negatively affect the phosphorylation of Smad2.
Molecular Weight: 441, 535
