Product Overview
Lysicamine | TN4471 | TargetMol Chemicals
CAS: 15444-20-9
Smiles: COc1cc2ccnc3C(=O)c4ccccc4-c(c1OC)c23
Formula: C18H13NO3
Pathway: Immunology/Inflammation|||Microbiology/Virology
Target: IL Receptor|||Antifection
Receptor: N/A
Bioactivity: Lysicamine shows significant antioxidant capacity in the ORAC(FL) assay and it is active against S. epidermidis and C. dubliniensis, with MIC values in the range 12.5-100 microg mL(-1). Lysicamine has antimicrobial and anti-inflammation activity, the minimum inhibitory concentrations of the pour component (Streptococcus mutans, Porphyromonas gingivalis, Actinobacillus actinomycetemcomitans and Candida albicans.) is less than 5mg/ml for all four microorganisms and the minimum concentration with anti-inflammation is 0.2mg/ml for both IL-8 and IL-6. Lysicamine has antileishmanial activity. It can significantly inhibit the proliferation of melanoma cells, it has antioxidative activity and chemopreventive activity in skin melanoma cells.
Molecular Weight: 291, 3