Product Overview
M-525 | T15831 | TargetMol Chemicals
CAS: 2173582-08-4
Smiles: COC(=O)N[C@H]1CCC[C@@H]1[C@@](C#N)(C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)C2CN(C2)C(=O)\C=C\CN(C)C)CC1)c1cccc(F)c1
Formula: C39H51FN6O5S
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: M-525 binds to menin (IC50: 3 nM) and achieves low nanomolar potencies in cell growth inhibition and in the suppression of MLL regulated gene expression in MLL leukemia cells. M-525 is a first-in-class, highly potent, irreversible, and covalent menin-MLL protein-protein interaction inhibitor. It has an Anti-leukemia activity.
Molecular Weight: 734, 93
