Product Overview
m-Chlorophenylbiguanide hydrochloride | T22959 | TargetMol Chemicals
CAS: 2113-05-5
Smiles: Cl.NC(=N)NC(=N)Nc1cccc(Cl)c1
Formula: C8H11Cl2N5
Pathway: GPCR/G Protein|||Neuroscience
Target: 5-HT Receptor
Receptor: N/A
Bioactivity: m-Chlorophenylbiguanide hydrochloride is a 5-HT3 receptor agonist. m-Chlorophenylbiguanide hydrochloride selectively binds 5-HT3(Ki: 0.002 µM) over 5-HT1A(Ki: 10 µM) and 5-HT2(Ki: 10 µM) receptors but also binds to high and low affinity sites on the dopamine transporter(DAT; IC50s: 0.4 and 34.8 µM, respectively, in rat caudate putamen synaptosomal membranes).
Molecular Weight: 248, 11
