Product Overview
Mabuterol free base | T27970 | TargetMol Chemicals
CAS: 56341-08-3
Smiles: CC(C)(C)NCC(O)c1cc(Cl)c(N)c(c1)C(F)(F)F
Formula: C13H18ClF3N2O
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Mabuterol is a selective agonist of β2 adrenoreceptor with no beta 1-stimulation. Mabuterol inhibited the positive inotropic effect of isoprenaline at 10(-7) g/ml and decreased the maximum driving frequency at 3 X 10(-6) g/ml. Mabuterol was 3 times more potent in relaxing the isolated rat uterus, but 700 times less potent than isoprenaline in relaxing the rabbit jejunum. Mabuterol (p.o.) depressed the intestinal propulsion and was equipotent to isoprenaline and 2.5 times less potent than salbutamol.
Molecular Weight: 310, 75
