Product Overview
Mahanine | TN6198 | TargetMol Chemicals
CAS: 28360-49-8
Smiles:
Formula: C23H25NO2
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Mahanine has effects on the activation of the apoptotic pathway in human leukemia U937 cells, causes the mitochondrial membranes to lose their permeability, resulting in caspase-3 activation and apoptosis. Mahanine can reverse an epigenetically silenced gene, RASSF1A in prostate cancer cells by inhibiting DNMT activity that in turn down-regulates a key cell cycle regulator, cyclin D1, is an encouraging therapeutic choice for advanced prostatic cancer.
Molecular Weight: N/A