Product Overview
Mal-PEG4-VC-PAB-DMEA-PNU-159682 | T18292 | TargetMol Chemicals
CAS: 2259318-52-8
Smiles: [H][C@]12O[C@]3([H])[C@H](C)O[C@]([H])(C[C@]3([H])N1CCO[C@@H]2OC)O[C@H]1C[C@@](O)(Cc2c(O)c3C(=O)c4cccc(OC)c4C(=O)c3c(O)c12)C(=O)COC(=O)N(C)CCN(C)C(=O)OCc1ccc(NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCNC(=O)CCN2C(=O)C=CC2=O)C(C)C)cc1
Formula: C74H98N10O27
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: Mal-PEG4-VC-PAB-DMEA-PNU-159682, a drug-linker conjugate for ADC, consists the ADC linker Mal-PEG4-VC-PAB and a potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 includes metabolites of nemorubicin (MMDX) from liver microsomes and ADC cytotoxin PNU-159682[1].
Molecular Weight: 1559, 641
