Product Overview
Mal-Phe-C4-VC-PAB-MMAE | T18303 | TargetMol Chemicals
CAS: 2259318-51-7
Smiles: [H][C@]([C@@H](C)CC)([C@@H](CC(=O)N1CCC[C@@]1([H])[C@H](OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)c1ccccc1)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C(=O)OCc1ccc(NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCCc2ccc(cc2)N2C(=O)C=CC2=O)C(C)C)cc1)C(C)C
Formula: C72H105N11O15
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: Mal-Phe-C4-VC-PAB-MMAE is made by MMAE conjugated to Mal-Phe-C4-VC-PAB linker. Monomethyl auristatin E (MMAE), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate.
Molecular Weight: 1364, 694
