Mal-VC-PAB-DM1 | T18305

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Mal-VC-PAB-DM1 | T18305 | TargetMol Chemicals

CAS: 1464051-44-2

Smiles: [H][C@@]12C[C@@](O)(NC(=O)O1)[C@]([H])(OC)\C=C/C=C(C)\Cc1cc(OC)c(Cl)c(c1)N(C)C(=O)C[C@]([H])(OC(=O)[C@H](C)N(C)C(=O)OCc1ccc(NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCCCCN3C(=O)C=CC3=O)C(C)C)cc1)[C@]1(C)O[C@H]1[C@@H]2C

Formula: C61H82ClN9O17

Pathway: Others

Target: Others

Receptor: N/A

Bioactivity: Mal-VC-PAB-DM1 is a drug-linker conjugate for ADC with potent antitumor activity by using DM1 (a potent microtubule-disrupting agent), linked via the ADC linker Mal-VC-PAB [1].

Molecular Weight: 1248, 82

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