Product Overview
Maraviroc | T6016 | TargetMol Chemicals
CAS: 376348-65-1
Smiles: CC(C)c1nnc(C)n1[C@H]1C[C@@H]2CC[C@H](C1)N2CC[C@H](NC(=O)C1CCC(F)(F)CC1)c1ccccc1
Formula: C29H41F2N5O
Pathway: Immunology/Inflammation|||Microbiology/Virology|||Proteases/Proteasome
Target: HIV Protease|||CCR
Receptor: N/A
Bioactivity: Maraviroc is a C-C Chemokine Receptor Type 5 (CCR5) antagonist, and for MIP-1α(IC50=3.3 nM), MIP-1β (IC50=7.2 nM) and RANTES(IC50=5.2 nM).Maraviroc inhibits HIV-1 entry via CCR5 coreceptor interaction.
Molecular Weight: 513, 678