Product Overview
Mavelertinib | T21322 | TargetMol Chemicals
CAS: 1776112-90-3
Smiles: COc1nn(C)cc1Nc1nc(nc2n(C)cnc12)N1C[C@@H](F)[C@@H](C1)NC(=O)C=C
Formula: C18H22FN9O2
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Mavelertinib is an orally available inhibitor of the EGFR mutant form T790M, a secondarily acquired resistance mutation. Mavelertinib specifically binds to and inhibits EGFR T790M, which prevents EGFR-mediated signaling and leads to cell death in EGFR T790M-expressing tumor cells.
Molecular Weight: 415, 433