Product Overview
Mavorixafor | TQ0174 | TargetMol Chemicals
CAS: 558447-26-0
Smiles: NCCCCN(Cc1nc2ccccc2[nH]1)[C@H]1CCCc2cccnc12
Formula: C21H27N5
Pathway: Autophagy|||GPCR/G Protein|||Immunology/Inflammation
Target: CXCR
Receptor: N/A
Bioactivity: Mavorixafor is an effective and selective antagonist of CXCR4, with an IC50 value of 13 nM against CXCR4 125I-SDF binding. Mavorixafor inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells (IC50 = 1 nM) and PBMCs (IC50 = 9 nM).
Molecular Weight: 349, 482