MC-Sq-Cit-PAB-Dolastatin10 | T18315

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TMC-T18315
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MC-Sq-Cit-PAB-Dolastatin10 | T18315 | TargetMol Chemicals

CAS: 1941168-65-5

Smiles: CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)c1nccs1)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)[N+](C)(C)Cc1ccc(NC(=O)[C@H](CCCNC(N)=O)NC(=O)C2(CCC2)C(=O)NCCCCCN2C(=O)C=CC2=O)cc1)C(C)C

Formula: C70H105N12O12S

Pathway: Others

Target: Others

Receptor: N/A

Bioactivity: MC-Sq-Cit-PAB-Dolastatin10 is a drug-linker conjugate for ADC with potent antitumor activity by using Dolastatin10 (a tubulin polymerization inhibitor), linked via the ADC linker MC-Sq-Cit-PAB.

Molecular Weight: 1338, 74

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