Product Overview
Mc-Val-Cit-PAB-Cl | T18321 | TargetMol Chemicals
CAS: 1639351-92-0
Smiles: CC(C)[C@H](NC(=O)CCCCCN1C(=O)C=CC1=O)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(CCl)cc1
Formula: C28H39ClN6O6
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC50s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay). Mc-Val-Cit-PAB-Cl is a cleavable ADC linker.
Molecular Weight: 591, 11
