MC-Val-Cit-PAB-rifabutin | T18328

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TMC-T18328
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Product Overview

MC-Val-Cit-PAB-rifabutin | T18328 | TargetMol Chemicals

CAS: 2055900-34-8

Smiles: CO[C@H]1\C=C/O[C@@]2(C)Oc3c(C2=O)c2C4=NC5(CC[N+](CC(C)C)(Cc6ccc(NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCCCCN7C(=O)C=CC7=O)C(C)C)cc6)CC5)NC4=C(NC(=O)\C(C)=C/C=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)C(=O)c2c(O)c3C

Formula: C74H101N10O17

Pathway: Others

Target: Others

Receptor: N/A

Bioactivity: MC-Val-Cit-PAB-rifabutin is a drug-linker conjugate for ADC with potent antitumor activity by using rifabutin (an DNA-dependent RNA polymerase inhibitor), linked via the ADC linker MC-Val-Cit-PAB.

Molecular Weight: 1402, 674

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