Product Overview
Mcl1-IN-8 | T16030 | TargetMol Chemicals
CAS: 678158-55-9
Smiles: OCCN1CCN(CC1)C1=NC(=O)\C(S1)=C\c1ccc(cc1)-c1ccccc1
Formula: C22H23N3O2S
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: Mcl1-IN-8 is an Mcl-1-PUMA interface inhibitor (Ki: 0.3 μM). In cancer cells, Mcl1-IN-8 shows dual activity on reducing PUMA-dependent apoptosis while deactivating Mcl-1-mediated anti-apoptosis.
Molecular Weight: 393, 51
