Product Overview
MEN 11270 | TP1999 | TargetMol Chemicals
CAS: 235082-52-7
Smiles:
Formula: C60H90N20O11S
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Peptide antagonist of the B2 bradykinin receptor (pKi = 10.3); conformationally constrained cyclized analog of HOE 140. Blocks hypotension and bronchoconstriction in vivo. Displays selectivity for B2 over 29 other receptors and ion channels (pIC50 < 5.5).
Molecular Weight: 1299, 56
