Merbarone | T28017

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€100.00
SKU:
TMC-T28017
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Product Overview

Merbarone | T28017 | TargetMol Chemicals

CAS: 97534-21-9

Smiles: O=CN(C1C(=O)NC(=S)NC1=O)c1ccccc1

Formula: C11H9N3O3S

Pathway: N/A

Target: N/A

Receptor: N/A

Bioactivity: Merbarone is a Type II DNA topoisomerase inhibitor. Merbarone inhibits the catalytic activity of human topoisomerase IIalpha by blocking DNA cleavage. Merbarone induces activation of caspase-activated DNase and excision of chromosomal DNA loops from the nuclear matrix. Merbarone induces apoptosis in CEM cells through activation of ICE/CED-3-like protease.

Molecular Weight: 263, 27

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