MF-766 | T9622

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€375.00 - €4,000.00
SKU:
TMC-T9622
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Product Overview

MF-766 | T9622 | TargetMol Chemicals

CAS: 1050656-06-8

Smiles: OC(c1ccc(C2(CC2)NC(c2c3n(Cc4ccc(C(F)(F)F)cc4)ccc3ccc2)=O)cc1)=O

Formula: C27H21F3N2O3

Pathway: GPCR/G Protein|||Immunology/Inflammation

Target: Prostaglandin Receptor

Receptor: N/A

Bioactivity: MF-766 is a highly potent, selective and orally active EP4 antagonist with a Ki of 0.23 nM. It behaves as a full antagonist with an IC50 of 1.4 nM (shifted to 1.8 nM in the presence of 10% HS) in the functional assay. It can be used for cancer and inflammation diseases research[1][2].

Molecular Weight: 478, 46

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