Product Overview
MI-1481 | T24463 | TargetMol Chemicals
CAS: 1887178-64-4
Smiles: Cc1c(CN2CCC(CC2)Nc2ncnc3sc(CC(F)(F)F)cc23)ccc2n(C[C@@H]3CNC(=O)CO3)c(cc12)C#N
Formula: C29H30F3N7O2S
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: MI-1481 is an effective MML1 inhibitor (IC50: 3.6 nM). MI-1481 showed very potent inhibition of the menin-MLL1 interaction (IC50: 3.6 nM). MI-1481 also demonstrates pronounced activity in MLL leukemia cells and in vivo in MLL leukemia models.
Molecular Weight: 597, 66
