Product Overview
MID-1 | T8773 | TargetMol Chemicals
CAS: 312608-54-1
Smiles: CCOc1ccc(cc1)C(=O)Nc1ncc(s1)[N+]([O-])=O
Formula: C12H11N3O4S
Pathway: Others|||Tyrosine Kinase/Adaptors
Target: Others|||IGF-1R
Receptor: N/A
Bioactivity: MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction. It disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake
Molecular Weight: 293, 3
