Product Overview
Midodrine hydrochloride | T1577 | TargetMol Chemicals
CAS: 3092-17-9
Smiles: Cl.COc1cc(C(O)CNC(=O)CN)c(OC)cc1
Formula: C12H19ClN2O4
Pathway: GPCR/G Protein|||Neuroscience
Target: Adrenergic Receptor
Receptor: N/A
Bioactivity: Midodrine is converted to its active metabolite, desglymidodrine by deglycination reaction. Desglymidodrine selectively binds to and activates alpha-1-adrenergic receptors of the arteriolar and venous vasculature. This causes smooth muscle contraction and leads to an elevation of blood pressure. Desglymidodrine diffuses poorly across the blood-brain barrier and is therefore not associated with effects on the central nervous system. Midodrine Hydrochloride is the hydrochloride salt form of midodrine, a direct-acting prodrug and sympathomimetic agent with antihypotensive properties.
Molecular Weight: 290, 74
