Product Overview
Milademetan free base | T24466 | TargetMol Chemicals
CAS: 1398569-75-9
Smiles: O=C([C@H](N1)[C@H](C2=C(F)C(Cl)=NC=C2)[C@]3(C(NC4=C3C=CC(Cl)=C4)=O)C51CCC(C)(C)CC5)N[C@H]6CO[C@H](C(N)=O)CC6
Formula: C30H34Cl2FN5O4
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Milademetan (DS-3032b or DS-3032) is a potent and selective MDM2 inhibitor with potential antineoplastic activity. Milademetan (p.o.) binds to and prevents the binding of MDM2 protein to the transcriptional activation domain of the tumor suppressor protein p53.
Molecular Weight: 618, 53