Product Overview
MK-8325 | T24480 | TargetMol Chemicals
CAS: 1334314-19-0
Smiles: Cl.Cl.COC(=O)N[C@@H](C(C)C)C(=O)N1CC(F)(F)C[C@H]1c1ncc([nH]1)-c1ccc(cc1)-c1ccc2c3[nH]c(nc3ccc2c1)[C@@H]1C[Si](C)(C)CN1C(=O)[C@@H](NC(=O)OC)C(C)C
Formula: C43H54Cl2F2N8O6Si
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: MK-8325 is an effective HCV NS5A inhibitor. It also has excellent replicon activity across multiple genotypes. In vitro and in vivo assays showed MK-8325 to be orally bioavailable with pharmacokinetics suitable for once-daily dosing in patients and good overall ADME profiles.
Molecular Weight: 915, 94
