Product Overview
ML-9 | T16104 | TargetMol Chemicals
CAS: 105637-50-1
Smiles: Cl.Clc1cccc2c(cccc12)S(=O)(=O)N1CCCNCC1
Formula: C15H18Cl2N2O2S
Pathway: Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling
Target: Myosin|||Akt
Receptor: N/A
Bioactivity: ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively. ML-9 is a selective and effective inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK), and stromal interaction molecule 1 (STIM1) activity. ML-9 causes autophagy by stimulating autophagosome formation and inhibiting their degradation.
Molecular Weight: 361, 28
