Product Overview
ML318 | T8533 | TargetMol Chemicals
CAS: 1610516-67-0
Smiles: Fc1ccc(cc1)C(C#N)c1cccc(n1)C(F)(F)F
Formula: C14H8F4N2
Pathway: Microbiology/Virology|||Others
Target: Others|||Antibiotic
Receptor: N/A
Bioactivity: ML318 is a biaryl nitrile PvdQ acylase inhibitor (IC50 of 20 nM for binding in the acyl-binding site). ML318 inhibits P. aeruginosa (PAO1) with IC50 of 19 μM. ML318 prevents pyoverdine production and limits the growth of P. aeruginosa under iron-limiting conditions.
Molecular Weight: 280, 226