Product Overview
ML753286 | T16113 | TargetMol Chemicals
CAS: 1699720-89-2
Smiles: [H][C@]12Cc3c([nH]c4cc(OC)ccc34)[C@H](CC(C)C)N1C(=O)[C@H](C)NC2=O
Formula: C20H25N3O3
Pathway: PI3K/Akt/mTOR signaling
Target: AMPK
Receptor: N/A
Bioactivity: ML753286 has high permeability and low to medium clearance in rodent and human liver S9 fractions. ML753286 is an orally active and selective inhibitor of BCRP (IC50: 0.6 μM). It is also stable in plasma across species.
Molecular Weight: 355, 438