Product Overview
MMV390048 | T16125 | TargetMol Chemicals
CAS: 1314883-11-8
Smiles: CS(=O)(=O)c1ccc(cc1)-c1cnc(N)c(c1)-c1ccc(nc1)C(F)(F)F
Formula: C18H14F3N3O2S
Pathway: Microbiology/Virology|||PI3K/Akt/mTOR signaling
Target: Parasite|||PI4K
Receptor: N/A
Bioactivity: MMV390048 is an antimalarial agent and is a representative of a new chemical class of Plasmodium PI4K inhibitor (Kdapp=0.3 μM). MMV390048 binds to the ATP binding site of Plasmodium PI4K and does not bind to other P. falciparum and human kinases apart from human PIP4K2C, thus alleviating potential kinase-mediated safety concerns.
Molecular Weight: 393, 38